- Healthy red blood cells are round and they move through small blood vessels carrying oxygen to all parts of the body.
- In SCD, the red blood cells become hard and sticky and look like a C-shaped farm tool called a “sickle”.
- Sickle cells die early, which causes a constant shortage of red blood cells.
What causes SCD?
- Point mutation in beta globulin gene changing Glu→Val at position 6 in the Beta Globin chain of hemoglobin, results…