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Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

Caspase inhibitors (CI) selectively protect normal cells from chemotherapy-induced apoptosis, without protection multidrug-resistant cancer cells. Flavopiridol (shown in red, as a cytotoxic/lethal drug) can induce apoptosis. The caspase inhibitor Z-DEVD-fmk (green) can block apoptosis but multidrug-resistant cancer cells pump it out. Credit: Oncotarget (2023). DOI:…


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Kering Eyewear Acquires Manufacturing Company UNT

Kering Eyewear Acquires Manufacturing Company UNT

Silver Lake and CPP Investments to acquire Qualtrics for $12.5 billion

Silver Lake and CPP Investments to acquire Qualtrics for $12.5 billion