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Scientists identify how some angiogenic drugs used to treat cancer and heart disease cause vascular disease

Scientists identify how some angiogenic drugs used to treat cancer and heart disease cause vascular disease
Drugs that inhibit Delta-Notch signaling trigger significant alterations in vascular architecture and induce the expression of genes involved in angiogenesis. The changes in vascular architecture do not disappear when expression of the angiogenesis-related genes is blocked. Credit: CNIC

Research by scientists at the Centro Nacional de…

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