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Phenylalanine degrading probiotics are a more effective live biotherapeutic for phenylketonuria

Phenylalanine degrading enzymes-displayed probiotics are more effective live biotherapeutic for phenylketonuria

Patients with phenylketonuria are unable to metabolize phenylalanine in the liver as healthy people do. They metabolize phenylalanine in the intestine through oral administration of the engineered probiotic TYS8500. Credit: Science China Press

Research published recently in Science China Life Sciences led by Prof. Sheng Yang from the Key…


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