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Lab-grown ‘mini-guts’ could help in development of new and more personalized treatments for Crohn’s disease

Lab-grown 'mini-guts' could help in development of new and more personalized treatments for Crohn's disease

Immunofluorescence spinning disc microscopy images of organoids. Credit: Thomas Dennison/University of Cambridge

Cambridge scientists have grown ‘mini-guts’ in the lab to help understand Crohn’s disease, showing that ‘switches’ that modify DNA in gut cells play an important role in the disease and how it presents in patients.


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