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Increased concentrations of GPNMB in blood samples could be biomarker for Parkinson’s disease

by Editor August 21, 2022, 4:51 am 1.4k Views

Increased concentrations of GPNMB in blood samples could be biomarker for Parkinson’s disease

Haplotypes associated with PD result in increased expression of GPNMB, encoding GPNMB. GPNMB interacts with aSyn, with effects on aSyn expression at the synapse, cellular uptake of fibrillar aSyn, and development of aSyn pathology in neurons. Together, these cellular processes mediate risk for development and progression of PD. Created with BioRender.com. PFF, preformed…

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