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in Health

Genome-wide intricacies of cancer inhibitor untangled

by Editor June 6, 2022, 1:31 pm 1.5k Views

Genome-wide intricacies of cancer inhibitor untangled

MYCi975 selectively affects MYC binding to promoters and target gene expression. (A) Heatmap representation of ChIP-seq signal at annotated promoters of MYCi975-sensitive sites (types 1, 2, and 3). (B) Log₂(fold change) of genes for each type as calculated from differential gene expression analysis of DMSO- versus 48-hour MYCi975-treated 22Rv1 cells. These genes have an…

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