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COVID-19 mutations accelerated by virus-fighting enzyme in human cells, according to new research

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COVID-19 mutations accelerated by virus-fighting enzyme in human cells, according to new research

Local sequence context at the APOBEC-edited C sites on SARS-CoV-2 RNA. (A) Local sequences around the significantly edited target C sites (± 5 nucleotides from target C at position 0) by A1 + A1CF, A3A, or A3G. The editing level of each C site was normalized to the Ctrl, and only sites with 3 × or higher editing levels than the normalized value were defined as…

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