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Changed gene expression after heart surgery extends cardiomyocyte regeneration

Changed gene expression after heart surgery extends cardiomyocyte regeneration

Jianyi “Jay” Zhang. Credit: UAB

While lower vertebrates can repair their adult hearts after a heart attack, mammals—including humans—cannot. The ability to regenerate dead muscle tissue in mammalian hearts disappears just a few days after birth because the heart muscle cells, called cardiomyocytes, exit the cell cycle.


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