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A predictive biomarker of response to therapy in patients with microsatellite stable metastatic colorectal cancer

VHIO-led study unveils predictive biomarker of response to therapy in patients with microsatellite stable BRAFV600E metastatic c

A total of 166 patients with mCRCBRAF-V600E were included in the study from discovery (n = 46), validation (n = 52) and control (n = 68) cohorts. WES of germline DNA, baseline tumor DNA and/or baseline plasma cfDNA from 28 patients was performed. Targeted NGS was used to assess RNF43 tumor mutation status for the 18 remaining patients from the discovery cohort…


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Vaquera RTW Spring 2023

Vaquera RTW Spring 2023

Esteban Sinisterra, Esteban Sinisterra fashion designer, Esteban Sinisterra Colombian vice-president

Young Black designer dresses Colombian vice-president in ‘resistance’ fashion