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Scientists solve 18-year-old mystery and find the once-elusive source of a critical T cell population

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Scientists solve 18-year-old mystery and find the once-elusive source of a critical T cell population

Presence of Tcf7+ CD8+ T cells during the primary response to infection. (A) Experimental schematic: Naïve P14 cells (CD45.2) were transferred into congenically distinct B6 mice (CD45.1) that were subsequently infected with LCMV (Arm or WE strain). On the indicated day of infection, P14 cells present in the spleen (unless indicated otherwise) were characterized using…

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