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Researchers discover functional compensatory effects in Treg cells

Prof. Yi Sun's team found the functional compensation between Ube2m-Rbx1 and Ube2f-Sag axes of the neddylation-CRLs in Treg cells

Fig. 1. Enhanced inflammation phenotype and transcription alterations caused by Ube2m and Ube2f-deficiency compared to Ube2m-deficiency in Treg cells. Credit: Research (2023). DOI: 10.34133/research.0212

Professor Yi Sun’s team at the Zhejiang University report a functional compensatory effect between the Ube2m-Rbx1 and Ube2f-Sag axes of the…


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