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Dopamine control: Turning off one ion channel made mice smarter. Turning off another made them more motivated.

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Researchers find switches that control dopamine in brain

A mosaic expression of two ion channels in dopamine neurons of a mouse’s brain. Researchers have found a way to control dopamine release. Credit: Larry Zweifel

Researchers have identified two ion channel switches that regulate the release of dopamine in the brain, a first step that might one day lead to therapeutics for a wide range of diseases…

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