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3D genome architecture influences SCID-X1 gene therapy success

3D genome architecture influences SCID-X1 gene therapy success

Genomic signatures of lentiviral VIS. (A) Circular projection of the human genome with integration sites from patients 1, 2, 3, and 6. Gene names near integration site hotspots are listed in the inner circle. (B) Overlap of VIS hotspots in patients. The numbers along the diagonal represent the number of hotspots in individual patients, and the other numbers indicate…


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Luxury Fashion’s Designer Diversity Problem Persists

Luxury Fashion’s Designer Diversity Problem Persists

Almara on a boat, wearing a life jacket and sunglasses, smiling

I’m best friends with my ex – here’s how I deal with jealous partners